We can help. We have a unique understanding of the role that dermal fat cells play in facial fat fitness. Our concept is published in Europe’s leading plastic surgery journal.
Facial fitness
is something
you achieve
Volume deficits happen when dermal
fat cells don't regenerate properly
Eye Hollowing
Mouth Erosion
Cheek Erosion
Factors that Slow Down Regeneration
Sun Exposure
UV rays create inflammation on the skin surface which causes downstream damage to dermal adipocytes (PMID: 27665714).
Age
With age, pre-adipocytes are still converting to mature adipocytes but this process requires a stronger signal PMID: 17507194.
Procedures
Injecting the body with foreign substances like engineered botulinum toxin, cross-linked hyaluronic acid and poly-L lactic acid filler may trigger inflammatory responses that can suppress adipogenesis. In terms of frequency, poly-L lactic acid, then hyaluronic acid then botulinum toxin. PMIDs: 33797747, 20564542, and 21903293.
Dynamic Facial Movement
UV rays create inflammation on the skin surface which causes downstream damage to dermal adipocytes (PMID: 27665714).
Excessive Exercise
All exercise suppresses new fat cell formation through acute inflammation and also through dynamic force and prolonged exercise has a greater effect than moderate exercise PMID: 32230849.
Poor Circulation
Growth factors are delivered to the skin through the circulation. Growth factors such as VEGFA are fundamental to sustaining a young skin phenotype. PMID: 35749494.
Diet
Protein drives regeneration of dermal adipocytes. Insufficient protein consumption is a leading cause of insufficient cell numbers. PMID: 27832138.
Products
The most common skincare ingredients – retin-A, resveratrol, and hyaluronic acid – are all anti-adipogenic. PMIDs 35171653, 17851734 and 31151314.
Hormones
Hormones play important roles in regulating fat cell health. Estrogen, for example, is important in maintaining adipogenesis. PMID: 35856485.
Skin becomes weak when
dermal fat cells grow too large
Bulging Cheek Bottom
Hanging Nasolabials
Droopy Jawline
Factors that Cause Cell Bloating
Volumne Loss
A reduction in the number of fat cells causes the size of the remaining fat cells to increases. PMID. 9333196.
High BMI
High BMI reflects increased nutrient storage and leads directly to enlarged fat cell size. PMID: 27895989.
Poor Lymphatics
Lymph fluid is largely comprised of lipid which is taken up by adipocytes, increasing their size. PMID. 34339353
Age
The increase in adipocyte size seen with age is a function of both higher BMI and lower regeneration rate. PMIDs. 30283987, 33878347.
Products
Oils in cosmetic products can be delivered to mature fat cells via the hair follicle, where they are taken up by mature fat cells. PMIDs. 33803716, 18492146.
Our holistic regimen
addresses the root causes
Protein-rich diet stimulates regeneration
Regular moderate exercise makes for small, dynamic fat cells
Removing excess lymph fluid protects fat cells from bloating
Stimulating circulation keeps growth factors flowing
Adipeau nurtures and tones the dermal fat cells
